Metal-free nitro-carbocyclization of 1,6-enynes with (t)BuONO and TEMPO.
نویسندگان
چکیده
A novel and convenient metal-free nitration and cyclization of 1,6-enynes has been developed. Two C-C bonds and one C-N bond were constructed in one process in this reaction. This transformation is proven to have relatively good functional-group applicability and can be scaled up to gram quantities in satisfactory yields. According to the following experimental facts and related literature reports, a radical pathway was involved in this transformation.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 31 شماره
صفحات -
تاریخ انتشار 2015